I really liked Nantes: great tramway, easy to get around, fun square in center with lots of activity, a vibrant college town. It's the western Loire - maybe 30 miles from the Atlantic. Also, we (and lots of other tourists) went to several of the chateaux in the area. Chenonceau was my favorite and we went to Cheverny and Chambord. I'd like to see Vouvray - not because I know anyhing about the city but because I like the wine. Sit outside somewhere in the Loire with an order of moules frites and a bottle of Muscadet (can I go with you?).