From the looks of it, there was Amtrak service to Louisville as
recently as 2003.
The trains arrived at
Union Station.
According to the first wikipedia link,
"The train was handicapped by inconvenient departure and arrival times and slow travel times, especially on the segment from Indianapolis south to Louisville. This segment was operated over the Louisville and Indiana Railroad, which had purchased the line from Conrail in 1994, and had a speed limit of 30 miles per hour (50 km/h) over most of the route due to its jointed rail. This made travel on the Kentucky Cardinal slower than automobile traffic on the parallel Interstate 65."I'm a bit of a train geek myself. In fact I worked for the C&NW for a few years in my misguided yoot. I agree it would be neat to have commuter service into Kentucky, but at those speeds you might as well walk.
I suspect the fact that Louisville is so accessible by plane and road contributes to the lack of trains. They simply can't compete.