Amy... I found this
http://www.ncdot.org/traffictravel/ it should help you with your travel plans. We always go through Knoxville since I have family there and then go up I-81 to Johnson City since I have a place there, it's about an hour over to Asheville from there and it's always a beautiful drive. From here though you can go another way and avoid Knoxville, but it looks to be about the same amount of time with the detour.
Chocolate Fetish is downtown
http://www.chocolatefetish.com/index.php and there are numerous great restaurants within walking distance and a really neat local art district around the Woolworth building down the street from CF. Another cool place to check is
http://www.greenlifegrocery.com, it's what Whole Foods should be...local, sustainable and affordable...I have more fun in that store!!
Ed...agree that salted caramel should be regulated...but keep your hands off my tiramisu! I'm looking forward to the Valentine's Day chocolate flavors they are making...if I don't get lured in by the caramel or tiramisu first!