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Hands down winner: Shady Lane Cafe at 4806 Brownsboro Rd. Dressed with everything, homemade chips on the side. Owned and run by some very, very nice people Bill & Susanne Smith. Not only a fantastic chef but an accomplished poet as well.
The Granville is great, but I have to go with Cumberland Brews. If you're not averse to eating bison, then theirs is the best hands down. I eat mine with bleu cheese and bacon.
"If more of us valued food and cheer and song above hoarded gold, it would be a merrier world."--J.R.R. Tolkien
Hey, we were there last night! Karen debated the burger vs steak frites, but she went w/ the steak. Tuna for moi. They were absolutely slammed and the kitchen backed up, but it's a great place to spend some time, so no problems there.
On a good day, the Bristol Burger can be a contendah. I love it that they put it on an English muffin. Also, W.W. Cousins for extreme quality meat and that amazing toppings bar, although I find the counter service there has become more and more fast-foodish over the years.
Gotta say, though, that Georgia Burger at L&N is da bomb. I also remember with great fondness when BBC St. Matthews all too briefly had a "Kobe" (doubtless really domestic Wagyu) burger.